Differential Diagnosis of Pigmented Lesions in the Oral Mucosa: A Clinical Based Overview and Narrative Review Pigmented Lesions of the Oral Mucosa Pocket Dentistry Melanotic macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight in single basal melanocytes; NO nests. More info like this in COM March 2009 Diagnosis UW School of Dentistry
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macule melanotic Oral Melanotic Macule: Symptoms and Treatment