Oral Melanotic Macule: Symptoms and Treatment Skinsight Melanotic macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight in single basal melanocytes; NO nests. More info like this in Pigmented macular lip lesion Clinical Advisor Lingual melanotic macule the first case report in an adult patient* Anais Brasileiros de Dermatologia
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