SHCGlutathione Vera Sidika's Changing Skin Tones "Back to Black?" Oral glutathione has been everyone on my timeline but does it actually work?! Looking at the data, its very modest to be honest. Id recommend sticking to what we know works fo hyperpigmentation in PDF) Evaluation of the Efficacy and Safety of Topical and Oral Glutathione in Treatment of Melasma PDF) Skin Lightening Treatments: The Effect of Intravenous Glutathione on the Disease States of Women