Dihexa (PNB 0408) c Met HGFR Activator MedChemExpress Dihexa (also known as PNB 0408) is an experimental small molecule derived from angiotensin IV. It was engineered to cross the bloodbrain barrier and has shown synaptogenic effects in preclinical models. The often quoted Molecular mechanism(s) of regulation(s) of c MET HGF signaling in head and neck cancer Molecular Cancer Springer Nature Link Correlation between hypoxia and HGF c MET expression in the management of pancreatic cancer ScienceDirect