BPC 157 has already hit the mainstream, but should it hit your bloodstream? BPC 157 is one of the most talked about peptides and for good reason. Originally discovered in the gastric juices of the stomach, this peptide helps protect and repair the intestinal lining and Multifunctionality and Possible Medical Application of the BPC 157 PeptideLiterature and Patent Review Peptide side effects no one talks about BPC 157 headaches. TB 500 fatigue. CJC Ipamorelin water retention. Most people quit. But 90% of the time it's the protocol, not the peptide.