Role of carnitine in disease Nutrition & Metabolism Springer Nature Link Acetyl L Carnitine (ALCAR) Supplement for Horses Mad Barn PDF) Improvement of insulin resistance via increase of GLUT4 and PPAR in metabolic syndrome induced rats treated with omega 3 fatty acid or l carnitine: ZAYED et al. There's a reason L carnitine keeps showing up in PCOS research Because PCOS is closely tied to insulin resistance, inflammation, and metabolic dysfunctionand L carnitine plays a role in energy metabolism and fat utilization.