Can Collagen Cause Constipation? Symptoms, Fixes & Safer Use Glutathione system enhancement for cardiac protection: pharmacological options against oxidative stress and ferroptosis Cell Death & Disease Glutathione Deficiency Symptoms: Is Poor Sleep Just the Beginning? Cardiology & Neurology Specialists located in Queens, Forest Hills and Brighton Beach, Brooklyn, NY Advanced Medical Care Leucovorin (also called folinic acid) is a folate analog and chemoprotective agent. It's used to rescue healthy cells from the toxic effects of high dose methotrexate, to enhance the effectiveness of fluorouracil (5 FU)