COM March 2009 Diagnosis UW School of Dentistry Solitary pigmentation of the tongue: lentigo simplex or pigmented fungiform papilla? ORAL MELANOSIS leading to the diagnosis of HIV infection. Despite being a weak association, any unexplained oral pigmentation in a high risk individual should make one suspect HIV associated oral melanosis and proceed Congenital Melanocytic Macule of the Tongue in a Newborn Cureus