The parent compounds of acetaminophen (US market in 1955 in the US as Tylenol and other products) were first discovered in 1886 (acetanilide) and 1887 (phenacetin). These were the earliest synthetic fever Acetaminophen detoxification in cucumber plants via induction of glutathione S transferases ScienceDirect Glutathione S acetaminophen conjugate 64889 81 2 Acetaminophen Toxicity Poisoning
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