HGF c Met pathway inhibition combined with chemotherapy increases cytotoxic T cell infiltration and inhibits pancreatic tumour growth and metastasis ScienceDirect What is dihexa, its mechanism of action via the HGF c Met pathway, and its safety and clinical use? HGF c Met pathway facilitates the perineural invasion of pancreatic cancer by activating the mTOR NGF axis Cell Death & Disease Dihexa targets neurotrophic factors like BDNF and NGF, which drive brain repair. By activating the c MET receptor, it helps cells take in nutrients and rebuildespecially in cases where recovery is slow or