ACNE] Warning to all those who supplement with B vitamins Be careful with excessive B12 : r SkincareAddiction Is B12 making you break out? It's possible. We've found in our own experience and in clinical studies that certain forms of vitamin B12 can trigger inflammatory acne for some individuals. Reply to @amisands6 hang in there pal #fyp #acne #b12 #b12injections #acneskin #skincareroutine Is B12 making you break out? It's possible. We've found in our own experience and in clinical studies that certain forms of vitamin B12 can trigger inflammatory acne for some individuals.