BPC 157 Oral Tablets Blue Skies Health & Wellness Clinic BPC 157 Oral vs Injection: Which Works Better? Healthletic Theres a lot of debate about whether BPC 157 needs to be injected or if the oral version works. The truth is, oral BPC 157 can be just as effective as injectablebut with one key adjustment. A small People talk about BPC 157 like it's one thing. It isn't. Oral BPC 157 stays local. It survives digestion long enough to act on the GI mucosa, then clears before it reaches systemic circulation.