Metabolism of ALCAR in brain. The mitochondrial membrane permeable Download Scientific Diagram Combined metabolic activators to treat mitochondrial dysfunction Mitochondrial dysfunction is a common feature of many human diseases and is emerging as a therapeutic target. Systems biology and multiomics approaches have revealed that Frontiers Dietary supplementation with L carnitine elevates intracellular carnitine levels and affects gene expression of SLC25A20 and COX4I1, as well as non mitochondrial respiration of bovine blood cells during systemic immune challenge A schematic diagram of the metabolic roles of carnitine in skeletal Download Scientific Diagram