Sex differences in glutathione metabolism and acetaminophen toxicity Dr. Chris Shade: Mercury Toxicity, Detoxification, and Glutathione Levels How do glutathione and Nacetylcysteine (NAC) compare regarding indications, dosing, effectiveness, and safety for acetaminophen toxicity, mucolytic therapy, and general antioxidant supplementation? Glutathione is such a critical soldier in our line of defense that our bodies make it themselves. We even have mechanisms that recycle and reuse it. But what happens when our toxic