Brown spots, especially on the lips, can be alarming to some. In some instances it can indicate rare oral mucosal melanoma, however in this case it was a non cancerous labial melanotic macule. Lenticular melanotic macule on the lower lip of a Laugier Hunziker Download Scientific Diagram a Melanotic macule at the wetdry line of the lower lip. b Melanotic Download Scientific Diagram Melanotic macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight in single basal melanocytes; NO nests. More info like this in