High homocysteine doesn't usually cause symptoms on its own, but it can signal vitamin deficiencies or other health issues and it's something you can check with a simple blood test Homocysteine: Genetics, High Homocysteine Levels, and Solutions Homocysteine: Genetics, High Homocysteine Levels, and Solutions Fitting homocysteine to disease models, as well as adjusting the models to the disease Journal of Molecular Medicine Springer Nature Link
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