Differential Diagnosis of Pigmented Lesions in the Oral Mucosa: A Clinical Based Overview and Narrative Review Melanotic macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight in single basal melanocytes; NO nests. More info like this in Differentiating between early melanomas and melanocytic nevi: A state of the art review ScienceDirect AD :: Annals of Dermatology
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labial melanotic macule vs melanoma PDF) Labial Melanotic Macule Diagnosed by Dermoscopy