Supplements and chronic pain: What does the research say? Some studies suggest possible benefits for: Acetyl L Carnitine (energy for cells; studied in diabetic nerve pain) Alpha Lipoic Acid (antioxidant; may ease nerve pain, Creatine monohydrate and L carnitine are two of the most researched supplements in the game., We are talking years. Decades. Proven over and over again., Creatine is your foundation., More strength. L Carnitine VS Creatine What's the Difference? Life Extension, Creatine & Acetyl L Carnitine, Energy Plus