“Melanosis” in the small and large intestine Melanosis coli is dark brown black pigmentation of colorectal mucosa associated with chronic use of laxatives containing anthraquinone. Examples of such laxatives include senna and rhubarb derivatives. Clinical Importance: There is no association Colorectal neoplasms in melanosis coli: a survey in Japan and a worldwide meta analysis International Journal of Colorectal Disease Springer Nature Link Melanosis Coli El Atlas Gastrointestinal gastrointestinalatlas.com
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