Oxidative pathways of alcohol metabolism. Alcohol is metabolized mainly Download Scientific Diagram Did you know that glutathione is our master antioxidant? Tylenol does absolutely carry the risk of liver damage and glutathione depletion, especially if overused or used alongside alcohol. Lower levels of glutathione Alcohol metabolism and why a few drinks linger longer than you think Your body processes >90% of ethanol in the liver, but the path creates toxic byproducts and drains key cofactors. 1 Cell to cell and organ to organ crosstalk in the pathogenesis of alcohol associated liver disease eGastroenterology