In G6PD deficiency (XR), we have increased oxidative damage to RBCs, leading to intravascular hemolysis with decreased serum haptoglobin. We have decreased NADPH production, which means decreased conversion of oxidized ( S S ) glutathione Glucose 6 phosphate dehydrogenase Wikipedia Understanding and Managing Glucose 6 Phosphate Dehydrogenase Deficiency ScienceDirect Glucose 6 Phosphate: Metabolism and Functions
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glutathione g6pd Role of G6PD in managing oxidative stress Glutathione peroxidase