A 48 hour fast can turn standard Paracetamol into acute liver failure. Fasting depletes Glutathione, leaving the liver defenseless against toxic NAPQI. Review the latest guidelines on BMJ Best Practice: https: bestpractice.bmj.com topics en us 1010 Paracetamolinduced hepatotoxicity at recommended dosage Kurtovic 2003 Journal of Internal Medicine Wiley Online Library The Case Severe high anion gap metabolic acidosis Kidney International Paracetamol Glucuronide an overview ScienceDirect Topics
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