The Fascinating Interplay between Growth Hormone, Insulin Like Growth Factor 1, and Insulin Local application of engineered insulin like growth factor I mRNA demonstrates regenerative therapeutic potential in vivo ScienceDirect IGF 1 LR3 does not promote growth in late gestation growth restricted fetal sheep American Journal of Physiology Endocrinology and Metabolism American Physiological Society Localized Igf 1 transgene expression sustains hypertrophy and regeneration in senescent skeletal muscle Nature Genetics
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