Glutathione: The Master Antioxidant Core Med Science Can you take glutathione without vitamin C? The simple answer: NO! Glutathione will not work without Vitamin C. Glutathione remains in two states, active and inactive. When it's in its active state, The Relationship Between Glutathione and Vitamin C: Can We Take Glutathione Without Vitamin C? Bubs Naturals Glutathione Injections: Benefits, Dosage, and Costs Hydrate IV Bar