Recruitment or activation of mast cells in the liver aggravates the accumulation of fibrosis in carbon tetrachloride induced liver injury ScienceDirect Effects of Dietary Components on Mast Cells: Possible Use as Nutraceuticals for Allergies? Mast cells are hypersensitive immune cells that release histamine and other inflammatory mediatorsoften in response to oxidative stress, environmental toxins, and immune imbalance. Many patients with MCAS have low levels of glutathione. Mast cell Wikipedia