Glutamylcysteine SynthetaseGlutathione Synthetase: Domain Structure and Identification of Residues Important in Substrate and Glutathione Binding Biochemistry Glutathione: your body's master antioxidant & detoxifier Glutathione is the 2nd most abundant molecule in the body, just after water. Its made from three amino acids: glycine, cysteine, & glutamate. MYCdriven inhibition of the glutamatecysteine ligase promotes glutathione depletion in liver cancer EMBO Reports Springer Nature Link Glutamate: Synthesis, transport, and supplement interactions