Structure and mechanism of mammalian thioredoxin reductase: The active site is a redox active selenolthiol selenenylsulfide formed from the conserved cysteine selenocysteine sequence PNAS Glutathione dependent thioredoxin reduction and lipoamide system support in vitro mammalian ribonucleotide reductase catalysis: a possible antioxidant redundancy Molecular Biology Reports Springer Nature Link Frontiers Assigning function to active site residues of Schistosoma mansoni thioredoxin glutathione reductase from analysis of transient state reductive half reactions with variant forms of the enzyme Thioredoxin Glutathione Reductase from Schistosoma mansoni: An Essential Parasite Enzyme and a Key Drug Target PLOS Medicine