Glutaminases regulate glutathione and oxidative stress in cancer Archives of Toxicology Springer Nature Link Glutamate Dehydrogenase 1 Signals through Antioxidant Glutathione Peroxidase 1 to Regulate Redox Homeostasis and Tumor Growth: Cancer Cell Glutathione is often called the body's master antioxidant for a reason. Research shows it plays a major role in detoxification, oxidative stress control, liver support, and neutralizing toxic alcohol byproducts like L glutamine for sickle cell disease: Knight or pawn? Alina Sadaf, Charles T Quinn, 2020