An analysis of Methylenetetrahydrofolate reductase and Glutathione S transferase omega 1 genes as modifiers of the cerebral response to ischemia BMC Neurology Springer Nature Link The Role of MTHFR in Thyroid Conditions: A Deep Dive into the Connection MTHFR Support Australia B vitamin polymorphisms and behavior: Evidence of associations with neurodevelopment, depression, schizophrenia, bipolar disorder and cognitive decline ScienceDirect The detox gene (MTHFR) is rendered inactive when your diet is high in meat. Our diet should be 80% plant based or higher.