Early research into L carnitine was often cited as underwhelming, showing negligible changes in muscle carnitine content and fat loss outcomes. However, these findings may have been limited by a short study window Medium chain fatty acid oxidation is independent of l carnitine in liver and kidney but not in heart and skeletal muscle American Journal of Physiology Gastrointestinal and Liver Physiology American Physiological Society L carnitine is a naturally occurring amino acid structure that is made in the human brain, liver, and kidneys. L carnitine plays a critical role in energy production, as it converts fat into energy. Liquid L Carnitine Core Nutritionals