1. Which detox pathways are you activating and in what order Detox is not a product it is a sequence of biochemical pathways. You must be able to explain Phase I biotransformation Pentose Phosphate Pathway made simple. This pathway has two major jobs: Generate NADPH Produce ribose 5 phosphate NADPH protects cells from oxidative stress and supports fatty acid, cholesterol, steroid, nitric oxide, and respiratory burst The Proto oncometabolite Fumarate Binds Glutathione to Amplify ROS Dependent Signaling: Molecular Cell The Electron Transport Chain and Pentose Phosphate Pathway biochemistry
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glutathione and nadph NADPH homeostasis in cancer: functions, mechanisms and therapeutic implications