Acetaminophen metabolism Acetaminophen or Tylenol Toxicity Lect 19 Pharmacology An Example of a Drug That Causes Toxicity Through the Formation of a Chemically Reactive Intermediate Mechanisms of Adverse Drug Reactions Pharmacovigilance Xia & He Publishing
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glutathione depletion paracetamol Paracetamol-Induced Hepatotoxicity ⚠️, Overdose → ↑ NAPQI formation → Glutathione depletion → Liver cell necrosis. Early N-acetylcysteine (NAC) can save the liver., #Pharmacology #mbbs #Hepatotoxicity